If you have a concrete ceiling, you can just drill the ceiling, put in a wall plug, and then screw in a hook for hanging the wire. If you want it to be more stable, hang with 2 hooks/wires.
If the frame and picture is very big and heavy, then you will need an expansion plug to secure the hook. These are used to hang heavy lights.
If you have false ceiling, you can use a butterfly plug to hold the hook. If you have enough space to climb on top of the false ceiling, you can just drill a tiny hole, string in the wire, and tie it to a flat object above the false ceiling, like a small plank. But remember that the false ceiling can sustain only a reasonable amount of weight. If it is too heavy, you will make a big hole in the false ceiling... and false ceilings are difficult to plaster smooth. Alternatively, you have to climb above the false ceiling to drill into the concrete, which is more painful.
