Went to Japan with my wife 2 weeks ago. I carried my 40D with 17-55mm f2.8, 50mm f.18, 580EXII, Filters(ND2, ND4, ND8, GND, CPL), Wireless remote & CF tripod with ballhead in a Lowepro Flipside 300.
HEAVY!! but it was all worth it.
#1 - the 1.8km forest trail to the snow monkey park...