On the Sandisk website, their Sandisk Extreme Plus have both microSDHC and SDHC.
Their microSDHC 16GB write speed is up to 30MB/sec where as the SDHC 16GB write speed is up to 60MB/sec.
For this case, there is a difference.
MicroSD are by nature, alot slower than SD card. This is inherited from the NAND die size.
If both have the same read/write speed (in 4k, and sequential), I will still go with the SD card because of reliability.
The connection between the microSD and adapter = 1 more point of failure, oxidisation, loss of energy resulting also in more heat.
There is a loss of power.